Over the rainbow to translational control

被引:14
作者
Gavis, ER [1 ]
机构
[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA
关键词
D O I
10.1038/87535
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Structures of the Puf domains from the Drosophila Pum and human Pum1 proteins reveal a novel function for a known structural repeat motif and exciting possibilities for the combinatorial assembly of complexes that regulate gene expression post-transcriptionally.
引用
收藏
页码:387 / 389
页数:3
相关论文
共 31 条
  • [1] Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos
    Asaoka-Taguchi, M
    Yamada, M
    Nakamura, A
    Hanyu, K
    Kobayashi, S
    [J]. NATURE CELL BIOLOGY, 1999, 1 (07) : 431 - 437
  • [2] PUMILIO IS ESSENTIAL FOR FUNCTION BUT NOT FOR DISTRIBUTION OF THE DROSOPHILA ABDOMINAL DETERMINANT NANOS
    BARKER, DD
    WANG, C
    MOORE, J
    DICKINSON, LK
    LEHMANN, R
    [J]. GENES & DEVELOPMENT, 1992, 6 (12A) : 2312 - 2326
  • [3] Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin α
    Conti, E
    Uy, M
    Leighton, L
    Blobel, G
    Kuriyan, J
    [J]. CELL, 1998, 94 (02) : 193 - 204
  • [4] A CCHC metal-binding domain in Nanos is essential for translational regulation
    Curtis, D
    Treiber, DK
    Tao, F
    Zamore, PD
    Williamson, JR
    Lehmann, R
    [J]. EMBO JOURNAL, 1997, 16 (04) : 834 - 843
  • [5] DISCRETE SEQUENCE ELEMENTS CONTROL POSTERIOR POLE ACCUMULATION AND TRANSLATIONAL REPRESSION OF MATERNAL CYCLIN-B RNA IN DROSOPHILA
    DALBY, B
    GLOVER, DM
    [J]. EMBO JOURNAL, 1993, 12 (03) : 1219 - 1227
  • [6] EDWARDS T, 2001, IN PRESS CELL
  • [7] Forbes A, 1998, DEVELOPMENT, V125, P679
  • [8] TRANSLATIONAL REGULATION OF NANOS BY RNA LOCALIZATION
    GAVIS, ER
    LEHMANN, R
    [J]. NATURE, 1994, 369 (6478) : 315 - 318
  • [9] The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs
    Groves, MR
    Hanlon, N
    Turowski, P
    Hemmings, BA
    Barford, D
    [J]. CELL, 1999, 96 (01) : 99 - 110
  • [10] Three-dimensional structure of the armadillo repeat region of beta-catenin
    Huber, AH
    Nelson, WJ
    Weis, WI
    [J]. CELL, 1997, 90 (05) : 871 - 882