Incorporation of [U-13C]glycerol defines plausible early steps for the biosynthesis of methylenomycin A in Streptomyces coelicolor A3(2)

被引：10

作者：

Challis, GL ^{[1
]}

Chater, KF ^{[1
]}

机构：

[1] John Innes Ctr Plant Sci Res, Dept Genet, Norwich NR4 7UH, Norfolk, England

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 10期

关键词：

D O I：

10.1039/b101615f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Incorporation of [U-C-13]glycerol into the linear plasmid-encoded secondary metabolite methylenomycin A, both intact and indirectly via metabolism to acetyl CoA, was observed in Streptomyces coelicolor suggesting plausible early biosynthetic steps for this unusual antibiotic.

引用

页码：935 / 936

页数：2

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