Gastric myoelectrical activity in healthy children and children with functional dyspepsia

被引:40
作者
Chen, JDZ [1 ]
Lin, XM [1 ]
Zhang, M [1 ]
Torres-Pinedo, RB [1 ]
Orr, WC [1 ]
机构
[1] INTEGRIS Baptist Med Ctr, Thomas N Lynn Inst Healthcare Res, Oklahoma City, OK 73112 USA
关键词
electrogastrography; functional dyspepsia; gastrointestinal motility; gastric emptying;
D O I
10.1023/A:1026661627304
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The aim of this study was to investigate abnormalities in pediatric patients with functional dyspepsia. Fifteen symptomatic pediatric patients diagnosed with functional dyspepsia and 17 aged-matched healthy controls were studied. Gastric myoelectrical activity was recorded using surface electrogastrography for 1 hr in the fasting state and 1 hr after a test meal. It was found that, in comparison with the controls, the children with functional dyspepsia had a lower percentage of 2- to 4-cpm slow waves in both fasting state (66.0 +/- 4.7% vs 79.7 +/- 3.1%, P < 0.07) and fed state (72.4 +/- 5.4% vs 85.0 +/- 2.9%, P < 0.04), and a significantly higher instability of the dominant frequency in both fasting state (0.50 +/- 0.05 vs 0.31 +/- 0.04, P < 0.01) and fed state (0.39 +/- 0.05 vs 0.25 +/- 0.03, P < 0.05). It was also found the postprandial increase in EGG dominant power in the patients was inversely correlated with the total symptom score (r = 0.63, P = 0.03). It was concluded that abnormal gastric myoelectrical activity may play a role in the pathogenesis of pediatric functional dyspepsia.
引用
收藏
页码:2384 / 2391
页数:8
相关论文
共 36 条
[1]   GLUCAGON-EVOKED GASTRIC DYSRHYTHMIAS IN HUMANS SHOWN BY AN IMPROVED ELECTROGASTROGRAPHIC TECHNIQUE [J].
ABELL, TL ;
MALAGELADA, JR .
GASTROENTEROLOGY, 1985, 88 (06) :1932-1940
[2]  
ABELL TL, 1991, EUR J GASTROEN HEPAT, V3, P63
[3]  
Alvarez WC, 1922, J AMER MED ASSOC, V78, P1116
[4]   DEFINITION AND INVESTIGATION OF DYSPEPSIA - CONSENSUS OF AN INTERNATIONAL AD-HOC WORKING PARTY [J].
BARBARA, L ;
CAMILLERI, M ;
CORINALDESI, R ;
CREAN, GP ;
HEADING, RC ;
JOHNSON, AG ;
MALAGELADA, JR ;
STANGHELLINI, V ;
WIENBECK, M .
DIGESTIVE DISEASES AND SCIENCES, 1989, 34 (08) :1272-1276
[5]   NUTRIENT-SPECIFIC MODULATION OF GASTRIC MECHANOSENSITIVITY IN PATIENTS WITH FUNCTIONAL DYSPEPSIA [J].
BARBERA, R ;
FEINLE, C ;
READ, NW .
DIGESTIVE DISEASES AND SCIENCES, 1995, 40 (08) :1636-1641
[6]  
Bortolotti M, 1990, J GASTROINTEST MOTIL, V2, P104, DOI 10.1111/j.1365-2982.1990.tb00015.x
[7]   A COMPUTERIZED DATA-ANALYSIS SYSTEM FOR ELECTROGASTROGRAM [J].
CHEN, J .
COMPUTERS IN BIOLOGY AND MEDICINE, 1992, 22 (1-2) :45-57
[8]  
CHEN J, 1992, AM J GASTROENTEROL, V87, P477
[9]  
Chen J.Z., 1994, ELECTROGASTROGRAPHY
[10]   SPECTRAL-ANALYSIS OF EPISODIC RHYTHMIC VARIATIONS IN THE CUTANEOUS ELECTROGASTROGRAM [J].
CHEN, JD ;
STEWART, WR ;
MCCALLUM, RW .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1993, 40 (02) :128-135