Biochemical risk factors and patient's outcome: the case of lipoprotein(a)

被引：22

作者：

Lippi, G

Guidi, G ^{[1
]}

机构：

[1] Univ Verona, Ctr Osped Clin Valeggio Mincio, Ist Chim & Microscopia Clin, Lab Anal Chim Clin & Microbiol, I-37067 Verona, Italy

[2] Univ Verona, Osped Policlin, Ist Chim & Microscopia Clin, I-37134 Verona, Italy

来源：

CLINICA CHIMICA ACTA | 1999年 / 280卷 / 1-2期

关键词：

lipoprotein(a); low density lipoproteins; athero-thrombotic diseases;

D O I：

10.1016/S0009-8981(98)00198-3

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Lipoprotein(a) (Lp(a)) is a genetic variant of low density lipoproteins and consists of the covalent association of the unique and enigmatic apolipoprotein(a) to apoliprotein B100. Despite the high degree of homology with low density lipoproteins, Lp(a) displays distinctive physicochemical properties, function and metabolism. The present article reviews the main biological and clinical evidences about the association between raised concentration of Lp(a) and atherothrombotic diseases and provides tentative guidelines to improve the clinical usefulness of Lp(a) measurements. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：59 / 71

页数：13

共 94 条

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