Tandem catalytic condensation and hydrogenation processes in ionic liquids

被引：16

作者：

Baidossi, M

Joshi, AV

Mukhopadhyay, S

Sasson, Y

机构：

[1] Hebrew Univ Jerusalem, Casali Inst Appl Chem, IL-91904 Jerusalem, Israel

[2] Univ Calif Berkeley, Dept Chem Engn, Berkeley, CA 94720 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 11期

关键词：

knoevenagel condensation; Pd/C; ionic liquids; hydrogenation;

D O I：

10.1016/j.tetlet.2005.01.092

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A domino reaction composed of a Knoevenagel condensation combined with a simultaneous catalytic hydrogenation is reported in an ionic liquid solvent under mild conditions (298-363 K and 300 kPa). No interference between the catalysts (Pd/C and amine acetate salt) of the two diverse steps was monitored. The product could be neatly extracted by diethyl ether and the solvent containing the catalysts could be recycled and reused five times without any loss in activity or selectivity. The same methodology in a common organic solvent such as DMA resulted in significant competing parallel hydrogenation of the aidehyde to alcohol. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1885 / 1887

页数：3

共 19 条

[1] Unexpected side reactions of imidazolium-based ionic liquids in the base-catalysed Baylis-Hillman reaction [J].