International day for the evaluation of abdominal obesity (IDEA) -: A study of waist circumference, cardiovascular disease, and diabetes mellitus in 168 000 primary care patients in 63 countries

被引:511
作者
Balkau, Beverley
Deanfield, John E.
Despres, Jean-Pierre
Bassand, Jean-Pierre
Fox, Keith A. A.
Smith, Sidney C., Jr.
Barter, Philip
Tan, Chee-Eng
Van Gaal, Luc
Wittchen, Hans-Ulrich
Massien, Christine
Haffner, Steven M.
机构
[1] INSERM, IFR69, U780, F-94807 Villejuif, France
[2] Univ Paris 11, Fac Med, Orsay, France
[3] Great Ormond St Hosp Sick Children, Cardiothorac Unit, London WC1N 3JH, England
[4] UCL, Inst Child Hlth & Grown Up Congenital Heart Dis, London, England
[5] Laval Hosp Res Ctr, Ste Foy, PQ, Canada
[6] Univ Hosp Jean Minjoz, Besancon, France
[7] Royal Infirm Edinburgh NHS Trust, Edinburgh, Midlothian, Scotland
[8] Univ N Carolina, Chapel Hill, NC USA
[9] Heart Res Inst, Sydney, NSW, Australia
[10] Natl Univ Singapore, Ctr Mol Epidemiol, Singapore 117548, Singapore
[11] Univ Antwerp Hosp, Antwerp, Belgium
[12] Tech Univ Dresden, Inst Clin Psychol & Psychotherapie, D-8027 Dresden, Germany
[13] Sanofi Aventis, Paris, France
[14] Univ Texas, Hlth Sci Ctr, San Antonio, TX 78285 USA
关键词
cardiovascular diseases; diabetes mellitus; epidemiology; obesity; risk factors;
D O I
10.1161/CIRCULATIONAHA.106.676379
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background - Abdominal adiposity is a growing clinical and public health problem. It is not known whether it is similarly associated with cardiovascular disease ( CVD) and diabetes mellitus in different regions around the world, and thus whether measurement of waist circumference ( WC) in addition to body mass index ( BMI) is useful in primary care practice. Methods and Results - Randomly chosen primary care physicians in 63 countries recruited consecutive patients aged 18 to 80 years on 2 prespecified half days. WC and BMI were measured and the presence of CVD and diabetes mellitus recorded. Of the patients who consulted the primary care physicians, 97% agreed to participate in the present study. Overall, 24% of 69 409 men and 27% of 98 750 women were obese ( BMI >= 30 kg/m(2)). A further 40% and 30% of men and women, respectively, were overweight ( BMI 25 to 30 kg/m(2)). Increased WC (>102 for men and >88 cm for women) was recorded in 29% and 48%, CVD in 16% and 13%, and diabetes mellitus in 13% and 11% of men and women, respectively. A statistically significant graded increase existed in the frequency of CVD and diabetes mellitus with both BMI and WC, with a stronger relationship for WC than for BMI across regions for both genders. This relationship between WC, CVD, and particularly diabetes mellitus was seen even in lean patients ( BMI < 25 kg/m(2)). Conclusions - Among men and women who consulted primary care physicians, BMI and particularly WC were both strongly linked to CVD and especially to diabetes mellitus. Strategies to address this global problem are required to prevent an epidemic of these major causes of morbidity and mortality.
引用
收藏
页码:1942 / 1951
页数:10
相关论文
共 39 条
  • [1] Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old
    Adams, Kenneth F.
    Schatzkin, Arthur
    Harris, Tamara B.
    Kipnis, Victor
    Mouw, Traci
    Ballard-Barbash, Rachel
    Hollenbeck, Albert
    Leitzmann, Michael F.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (08) : 763 - 778
  • [2] The metabolic syndrome - a new worldwide definition
    Alberti, KGMM
    Zimmet, P
    Shaw, J
    [J]. LANCET, 2005, 366 (9491) : 1059 - 1062
  • [3] Adipokine expression profile in adipocytes of different mouse models of obesity
    Boucher, J
    Castan-Laurell, I
    Daviaud, D
    Guigné, C
    Buléon, M
    Carpéne, C
    Saulnier-Blache, JS
    Valet, P
    [J]. HORMONE AND METABOLIC RESEARCH, 2005, 37 (12) : 761 - 767
  • [4] Visceral adiposity and risk of type 2 diabetes - A prospective study among Japanese Americans
    Boyko, EJ
    Fujimoto, WY
    Leonetti, DL
    Newell-Morris, L
    [J]. DIABETES CARE, 2000, 23 (04) : 465 - 471
  • [5] Rapid rise in the incidence of type 2 diabetes from 1987 to 1996 - Results from the San Antonio Heart Study
    Burke, JP
    Williams, K
    Gaskill, SP
    Hazuda, HP
    Haffner, SM
    Stern, MP
    [J]. ARCHIVES OF INTERNAL MEDICINE, 1999, 159 (13) : 1450 - 1456
  • [6] Carey VJ, 1997, AM J EPIDEMIOL, V145, P614, DOI 10.1093/oxfordjournals.aje.a009158
  • [7] Prevention conference VII - Obesity, a worldwide epidemic related to heart disease and stroke - Group III: Worldwide comorbidities of obesity
    Caterson, ID
    Hubbard, V
    Bray, GA
    Grunstein, R
    Hansen, BC
    Hong, YL
    Labarthe, D
    Seidell, JC
    Smith, SC
    [J]. CIRCULATION, 2004, 110 (18) : E476 - E483
  • [8] Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
    Cleeman, JI
    Grundy, SM
    Becker, D
    Clark, LT
    Cooper, RS
    Denke, MA
    Howard, WJ
    Hunninghake, DB
    Illingworth, DR
    Luepker, RV
    McBride, P
    McKenney, JM
    Pasternak, RC
    Stone, NJ
    Van Horn, L
    Brewer, HB
    Ernst, ND
    Gordon, D
    Levy, D
    Rifkind, B
    Rossouw, JE
    Savage, P
    Haffner, SM
    Orloff, DG
    Proschan, MA
    Schwartz, JS
    Sempos, CT
    Shero, ST
    Murray, EZ
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19): : 2486 - 2497
  • [9] Prognostic impact of body weight and abdominal obesity in women and men with cardiovascular disease
    Dagenais, GR
    Yi, QL
    Mann, JFE
    Bosch, J
    Pogue, J
    Yusuf, S
    [J]. AMERICAN HEART JOURNAL, 2005, 149 (01) : 54 - 60
  • [10] REGIONAL DISTRIBUTION OF BODY-FAT, PLASMA-LIPOPROTEINS, AND CARDIOVASCULAR-DISEASE
    DESPRES, JP
    MOORJANI, S
    LUPIEN, PJ
    TREMBLAY, A
    NADEAU, A
    BOUCHARD, C
    [J]. ARTERIOSCLEROSIS, 1990, 10 (04): : 497 - 511