Adjustment for baseline covariates: an introductory note

被引：17

作者：

Grouin, JM

Day, S

Lewis, J

机构：

[1] Hatch Green Cottage, Canterbury CT4 7LP, Kent, England

[2] Univ Rouen, F-78810 Feucherolles, France

[3] MHRA, London SW8 5NQ, England

来源：

STATISTICS IN MEDICINE | 2004年 / 23卷 / 05期

关键词：

D O I：

10.1002/sim.1646

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The purpose of this note is to provide the background to the material covered by the most recently adopted Committee on Proprietary Medicinal Products (CPMP) Points to Consider (PtC) document, the fifth in the series. This is a regulatory guideline on the topic of adjustment for baseline covariates in controlled clinical trials. It is reproduced in the following pages of this journal. © 2004 John Wiley & Sons, Ltd.

引用

页码：697 / 699

页数：3