Variable number tandem repeat dopamine transporter gene polymorphism and Parkinson's disease:: no association found

被引：31

作者：

Mercier, G ^{[1
]}

Turpin, JC ^{[1
]}

Lucotte, G ^{[1
]}

机构：

[1] Hop Maison Blanche, Serv Neurol, Mol Neurogenet Lab, F-51092 Reims, France

来源：

JOURNAL OF NEUROLOGY | 1999年 / 246卷 / 01期

关键词：

Parkinson's disease; dopamine transporter gene; variable number tandem repeat polymorphism association studies; French population;

D O I：

10.1007/s004150050304

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We studied a variable number of tandem repeat polymorphisms in the dopamine transporter gene in search of an association with Parkinson's disease in a French population. Five alleles were detected, consisting of 7, 8, 9, 10 and 11 copies of the 40-base pair repeat sequence, of which the 10-copy allele was the most common. There was no significant difference between the patients and the control subjects in the distribution frequencies of the alleles or genotypes, or in ages at onset in patients between the main allelic classes.

引用

页码：45 / 47

页数：3

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