Differential adsorption of nucleic acid bases: Relevance to the origin of life

被引：148

作者：

Sowerby, SJ

Cohn, CA

Heckl, WM

Holm, NG ^{[1
]}

机构：

[1] Stockholm Univ, Dept Geol & Geochem, SE-10691 Stockholm, Sweden

[2] LMU, Inst Kristallog & Angew Mineral, D-80333 Munich, Germany

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2001年 / 98卷 / 03期

关键词：

D O I：

10.1073/pnas.98.3.820

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The adsorption of organic molecules onto the surfaces of inorganic solids has long been considered a process relevant to the origin of life. We have determined the equilibrium adsorption isotherms for the nucleic acid purine and pyrimidine bases dissolved in water on the surface of crystalline graphite. The markedly different adsorption behavior of the bases describes an elutropic series: guanine > adenine > hypoxanthine > thymine > cytosine > uracil. We propose that such differential properties were relevant to the prebiotic chemistry of the bases and may have influenced the composition of the primordial genetic architecture.

引用

页码：820 / 822

页数：3

共 37 条

[1] NONENZYMATIC TRANSCRIPTION OF AN OLIGODEOXYNUCLEOTIDE-14 RESIDUES LONG [J].