Regional blood flow capillary permeability, and compartmental volumes: Measurement with dynamic CT - Initial experience

被引:159
作者
Brix, G [1 ]
Bahner, ML [1 ]
Hoffmann, UJ [1 ]
Horvath, A [1 ]
Schreiber, W [1 ]
机构
[1] German Canc Res Ctr, Heidelberg, Germany
关键词
blood; flow dynamics; computed tomography (CT); contrast measurement; diffusion study; head and neck neoplasms;
D O I
10.1148/radiology.210.1.r99ja46269
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];
摘要
Sequential computed tomographic scanning was performed in patients with neck tumors after contrast material administration. For data analysis,a pharmacokinetic two-compartment was employed that takes into account both capillary blood supply and bidirectional diffusion of the contrast agent across the capillary wall. This approach offers the possibility to quantitatively characterize tissue microcirculation with regional blood flow, capillary permeability, and relative compartmental volumes.
引用
收藏
页码:269 / 276
页数:8
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