Growth of an organic co-crystal upon a component subphase

被引：18

作者：

Seaton, Colin C. ^{[1
]}

Parkin, Andrew ^{[2
]}

Wilson, Chick C. ^{[2
]}

Blagden, Nicholas ^{[1
]}

机构：

[1] Univ Bradford, Sch Pharm, Inst Pharmaceut Innovat, Bradford BD7 1DP, W Yorkshire, England

[2] Univ Glasgow, Dept Chem, WestCHEM Res Sch, Glasgow G12 8QQ, Lanark, Scotland

来源：

CRYSTAL GROWTH & DESIGN | 2008年 / 8卷 / 02期

关键词：

D O I：

10.1021/cg060793m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report on the templated growth of 2:1 benzoic acid/isonicotinamide co-crystal on a benzoic acid subphase. The molecular basis for the template, registry between the phases, is presented. The template growth of behavior of the title compound was contrasted with that from melt and solution. This approach may be,applicable as a precursor for the synthesis of bulk composite crystals.

引用

页码：363 / 368

页数：6

共 32 条

[1]

Aakeröy CB, 2001, ANGEW CHEM INT EDIT, V40, P3240, DOI 10.1002/1521-3773(20010903)40:17<3240::AID-ANIE3240>3.0.CO

[2]

2-X

[3] Crystal engineering of the composition of pharmaceutical phases.: Do pharmaceutical co-crystals represent a new path to improved medicines? [J].

Almarsson, Ö ;

Zaworotko, MJ .

CHEMICAL COMMUNICATIONS, 2004, (17) :1889-1896

[4] Ordered aggregation of benzamide crystals induced using a "motif capper" additive [J].

Blagden, N ;

Song, M ;

Davey, RJ ;

Seton, L ;

Seaton, CC .

CRYSTAL GROWTH & DESIGN, 2005, 5 (02) :467-471

[5]

BOUAFEDE SJ, 1995, J AM CHEM SOC, V117, P7853

[6] DIRECTING POLYMORPH SELECTIVITY DURING NUCLEATION OF ANTHRANILIC ACID ON MOLECULAR SUBSTRATES [J].

CARTER, PW ;

WARD, MD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (02) :769-770

[7] Inclusion of the stable form of a polymorph within crystals of its metastable form [J].

Cashell, C ;

Sutton, D ;

Corcoran, D ;

Hodnett, BK .

CRYSTAL GROWTH & DESIGN, 2003, 3 (06) :869-872

[8] Stabilizing a solid-solid interface with a molecular-scale adhesive [J].

Davey, RJ ;

Williams-Seton, L ;

Lieberman, HF ;

Blagden, N .

NATURE, 1999, 402 (6763) :797-799

[9] From tectons to composite crystals [J].

Dechambenoit, P ;

Ferlay, S ;

Hosseini, MW .

CRYSTAL GROWTH & DESIGN, 2005, 5 (06) :2310-2312

[10] Solvent binding to benzamide crystals: Morphology, induced twinning and direct observation by surface X-ray diffraction [J].

Edgar, R ;

Schultz, TM ;

Rasmussen, FB ;

Feidenhans'l, R ;

Leiserowitz, L .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (04) :632-637

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