Quantum dots in bio-imaging: Revolution by the small

被引:121
作者
Arya, H
Kaul, Z
Wadhwa, R
Taira, K
Hirano, T
Kaul, SC
机构
[1] Natl Inst Adv Ind Sci & Technol, Gene Funct Res Ctr, AIST, Tsukuba, Ibaraki 3058562, Japan
[2] Natl Inst Adv Ind Sci & Technol, Inst Biol Resources & Funct, AIST, Tsukuba, Ibaraki 3058562, Japan
关键词
biomolecules; bio-imaging; quantum dots; sensitive; stable;
D O I
10.1016/j.bbrc.2005.02.043
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Visual analysis of biomolecules is an integral avenue of basic and applied biological research. It has been widely carried out by tagging of nucleotides and proteins with traditional fluorophores that are limited in their application by features such as photobleaching, spectral overlaps, and operational difficulties. Quantum dots (QDs) are emerging as a superior alternative and are poised to change the world of bio-imaging and further its applications in basic and applied biology. The interdisciplinary field of nanobiotechnology is experiencing a revolution and QDs as an enabling technology have become a harbinger of this hybrid field. Within a decade. research on QDs has evolved from being a pure science subject to the one with high-end commercial applications. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码:1173 / 1177
页数:5
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