On the molecular origins of the chronic myeloproliferative disorders: it all makes sense

被引:100
作者
Kaushansky, K [1 ]
机构
[1] Univ Calif San Diego, Dept Med, Div Hematol Oncol, San Diego, CA 92103 USA
关键词
D O I
10.1182/blood-2005-03-1287
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:4187 / 4190
页数:4
相关论文
共 45 条
  • [1] POLYCYTHEMIA-VERA - STEM-CELL AND PROBABLE CLONAL ORIGIN OF DISEASE
    ADAMSON, JW
    FIALKOW, PJ
    MURPHY, S
    PRCHAL, JF
    STEINMANN, L
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1976, 295 (17) : 913 - 916
  • [2] Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
    Ang, SO
    Chen, H
    Hirota, K
    Gordeuk, VR
    Jelinek, J
    Guan, YL
    Liu, EL
    Sergueeva, AI
    Miasnikova, GY
    Mole, D
    Maxwell, PH
    Stockton, DW
    Semenza, GL
    Prchal, JT
    [J]. NATURE GENETICS, 2002, 32 (04) : 614 - 621
  • [3] Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity
    Argetsinger, LS
    Kouadio, JLK
    Steen, H
    Stensballe, A
    Jensen, ON
    Carter-Su, C
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2004, 24 (11) : 4955 - 4967
  • [4] Axelrad AA, 2000, BLOOD, V96, P3310
  • [5] Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    Baxter, EJ
    Scott, LM
    Campbell, PJ
    East, C
    Fourouclas, N
    Swanton, S
    Vassiliou, GS
    Bench, AJ
    Boyd, EM
    Curtin, N
    Scott, MA
    Erber, WN
    Green, AR
    [J]. LANCET, 2005, 365 (9464) : 1054 - 1061
  • [6] Cytokine receptor-independent, constitutively active variants of STAT5
    Berchtold, S
    Moriggl, R
    Gouilleux, F
    Silvennoinen, O
    Beisenherz, C
    Pfitzner, E
    Wissler, M
    Stocklin, E
    Groner, B
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (48) : 30237 - 30243
  • [7] Translational pathophysiology: a novel molecular mechanism of human disease
    Cazzola, M
    Skoda, RC
    [J]. BLOOD, 2000, 95 (11) : 3280 - 3288
  • [8] REGULATION OF PLATELET ACTIVATION IN-VITRO BY THE C-MPL LIGAND, THROMBOPOIETIN
    CHEN, JC
    HERCEGHARJACEK, L
    GROOPMAN, JE
    GRABAREK, J
    [J]. BLOOD, 1995, 86 (11) : 4054 - 4062
  • [9] CORREA PN, 1994, BLOOD, V83, P99
  • [10] Increased erythropoiesis in polycythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB
    Dai, CH
    Chung, IJ
    Krantz, SB
    [J]. EXPERIMENTAL HEMATOLOGY, 2005, 33 (02) : 152 - 158