Spinal fixation device: A 6-year postimplantation study

被引：14

作者：

Mohanty, M

Baby, S

Menon, KV

机构：

[1] Sree Chitra Tirunal Inst Med Sci & Technol, Div Implant Biol, Thiruvananthapuram 695012, Kerala, India

[2] Amritha Inst Med Sci & Res Ctr, Dept Orthoped, Kochi, Kerala, India

来源：

JOURNAL OF BIOMATERIALS APPLICATIONS | 2003年 / 18卷 / 02期

关键词：

spinal fixation device; metal; macrophages;

D O I：

10.1177/088532803034746

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Long-term tissue response to a metal device is described here. The components of a spinal fixation device were removed 6 years after implantation, following the need for revision surgery after a fall. Scanning electron microscopy (SEM) revealed changes in surface topography of the metal. Examination of the adjacent tissue showed a chronic inflammatory response with occasional metal debris. Immunohistochemistry identified the predominant macrophages and abundant neovascularization. The presence of macrophages in tissues adjacent to the implants, in an otherwise asymptomatic person, is noteworthy.

引用

页码：109 / 121

页数：13

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