PhyloPro: a web-based tool for the generation and visualization of phylogenetic profiles across Eukarya

被引：7

作者：

Xiong, Xuejian ^{[1
]}

Song, Hongyan ^{[1
]}

On, Tuan ^{[1
,2
]}

Lochovsky, Lucas ^{[1
]}

Provart, Nicholas J. ^{[3
,4
]}

Parkinson, John ^{[1
,2
,4
,5
]}

机构：

[1] Univ Toronto, Hosp Sick Children, Program Mol Struct & Funct, Toronto, ON M5G 1X8, Canada

[2] Univ Toronto, Dept Mol Genet, Toronto, ON M5G 1X8, Canada

[3] Univ Toronto, Dept Cell & Syst Biol, Toronto, ON M5G 1X8, Canada

[4] Univ Toronto, Ctr Anal Genome Evolut & Funct, Toronto, ON M5G 1X8, Canada

[5] Univ Toronto, Dept Biochem, Toronto, ON M5G 1X8, Canada

来源：

BIOINFORMATICS | 2011年 / 27卷 / 06期

关键词：

PROTEIN FUNCTION; PREDICTION;

D O I：

10.1093/bioinformatics/btr023

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Summary: With increasing numbers of eukaryotic genome sequences, phylogenetic profiles of eukaryotic genes are becoming increasingly informative. Here, we introduce a new web-tool Phylopro (http://compsysbio.org/phylopro/), which uses the 120 available eukaryotic genome sequences to visualize the evolutionary trajectories of user-defined subsets of model organism genes. Applied to pathways or complexes, PhyloPro allows the user to rapidly identify core conserved elements of biological processes together with those that may represent lineage-specific innovations. PhyloPro thus provides a valuable resource for the evolutionary and comparative studies of biological systems. Contact: jparkin@sickkids.ca.

引用

页码：877 / 878

页数：2

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