No evidence for association to the G72/G30 locus in an independent sample of schizophrenia families

被引：34

作者：

Mulle, JG

Chowdari, KV

Nimgaonkar, V

Chakravarti, A

机构：

[1] Johns Hopkins Univ, Sch Med, McKusick Nathans Inst Genet Med, Baltimore, MD 21205 USA

[2] Univ Pittsburgh, Med Ctr, Western Psychiat Inst & Clin, Pittsburgh, PA USA

来源：

MOLECULAR PSYCHIATRY | 2005年 / 10卷 / 05期

关键词：

D O I：

10.1038/sj.mp.4001619

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Multiple studies report positive associations between SNPs at the G72/G30 locus and schizophrenia, although published findings do not consistently implicate the same alleles. The authors investigated association at this locus for previously reported SNPs using a family-based sample. No association was demonstrated, despite prior evidence for linkage in this sample to chromosome 13q32. The authors concluded that the G72/G30 locus is unlikely to contribute to schizophrenia susceptibility in this sample. © 2005 Nature Publishing Group. All rights reserved.

引用

页码：431 / 433

页数：4

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