Ultra-performance liquid chromatography coupled with high-resolution quadrupole time-of-flight mass spectrometry analysis of the impact of bran-processing on the chemical profile of Radix Paeoniae Alba (Baishao)

被引：15

作者：

Zheng, Zhiyong ^{[1
]}

Cao, Gang ^{[2
]}

Wu, Xin ^{[2
]}

Chen, Xiaocheng ^{[3
]}

Cai, Baochang ^{[2
]}

机构：

[1] Zhejiang Chinese Med Univ, Dept Pharm, Wenzhou TCM Hosp, Wenzhou, Peoples R China

[2] Zhejiang Chinese Med Univ, Res Ctr TCM Proc Technol, Hangzhou, Zhejiang, Peoples R China

[3] Wenzhou Med Univ, Affiliated Hosp 1, Wenzhou, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 08期

基金：

中国国家自然科学基金;

关键词：

ultra-performance liquid chromatography coupled with high-resolution quadrupole time-of-flight mass spectrometry; processed mechanism; chemical profile; Radix Paeoniae Alba; RUBRA;

D O I：

10.1080/14786419.2014.985677

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

In this study, a rapid and versatile ultra-performance liquid chromatography coupled with high-resolution quadrupole time-of-flight mass spectrometry-based chemical profiling approach was applied to evaluate chemical constitution of crude and processed Radix Paeoniae Alba (RPA) samples. A total of 44 compounds were identified, among which the contents of 9 compounds in processed samples were obviously decreased and 8 compounds were increased. Furthermore, compound 28 was not found in RPA sample after stir-frying with wheat bran. The proposed method provided a chemical basis for exploring the processed mechanism of herbal medicine.

引用

页码：776 / 779

页数：4

共 12 条

[1]

Cheng M, 2012, CHIN WILD PLANT RESO, V6, P17

[2]

Du Xue-chun, 2012, Zhejiang Da Xue Xue Bao Yi Xue Ban, V41, P25

[3]

Quick comparison of Radix Paeonia Alba, Radix Paeonia Rubra, and Cortex Moutan by high performance liquid chromatography coupled with monolithic columns and their chemical pattern recognition [J].

He Chunnian ;

Peng Yong ;

Feng Yuxiong ;

Peng Bing ;

Wang Zhe ;

Xiao Peigen .

PHARMACOGNOSY MAGAZINE, 2012, 8 (31) :237-243

[4]

Huang Hao, 2012, Zhongguo Zhong Yao Za Zhi, V37, P3569

[5]

Huang Shan-jun, 2012, Yaoxue Xuebao, V47, P486

[6]

Luo NC, 2013, NAT PROD COMMUN, V8, P487

[7]

Qin KM, 2010, SCI SINICA, V6, P668

[8]

[秦昆明 Qin Kunming], 2013, [中国科学. 化学, Scientia Sinica Chimica], V43, P829

[9]

Tang H, 2011, J NANJING U TRADIT C, V27, P369

[10]

Detection of Sulfur-Fumigated Paeoniae Alba Radix in Complex Preparations by High Performance Liquid Chromatography Tandem Mass Spectrometry [J].

Wu, Jie ;

Shen, Hong ;

Xu, Jun ;

Zhu, Ling-Ying ;

Jia, Xiao-Bin ;

Li, Song-Lin .

MOLECULES, 2012, 17 (08) :8938-8954

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