Calcified cysticerci provoke perilesional edema and seizures

被引:71
作者
Nash, TE
Pretell, J
Garcia, HH
机构
[1] NIAID, Parasit Dis Lab, NIH, Bethesda, MD 20892 USA
[2] Inst Ciencias Neurol, Cysticercosis Unit, Lima, Peru
[3] Univ Peruana Cayetano Heredia, Dept Microbiol, Lima, Peru
[4] Univ Peruana Cayetano Heredia, Dept Pathol, Lima, Peru
关键词
D O I
10.1086/323670
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In cases of cysticercosis, seizures and other symptoms occur in persons with only calcified brain lesions. The presence of perilesional edema has been documented in association with calcified lesions in symptomatic patients, but the frequency of this complication and characteristics of the patients who develop it are not known. Patients in Peru and the United States with neurocysticercosis, documented by positive results of serological testing and with only calcified lesions as shown using computerized tomography, were studied using magnetic resonance imaging. Perilesional edema was observed in slightly more than one-third of the patients, and some patients had frequent, severely disabling episodes. Those with an increased proportion of enhancing calcified lesions were more likely to show perilesional edema. Edema around calcified lesions is common in this population and is associated with seizures and neurological morbidity.
引用
收藏
页码:1649 / 1653
页数:5
相关论文
共 22 条
[1]   Epilepsy and neurocysticercosis in an Andean community [J].
Cruz, ME ;
Schantz, PM ;
Cruz, I ;
Espinosa, P ;
Preux, PM ;
Cruz, A ;
Benitez, W ;
Tsang, VCW ;
Fermoso, J ;
Dumas, M .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 1999, 28 (04) :799-803
[2]   HISTOLOGICAL DESCRIPTION OF TOMOGRAPHIC-IMAGES OF TAENIA-SOLIUM CYSTICERCI IN PIG BRAINS [J].
DEALUJA, AS ;
GONZALEZ, D ;
CARBAJAL, JR ;
FLISSER, A .
CLINICAL IMAGING, 1989, 13 (04) :292-298
[3]   PROGNOSTIC FACTORS FOR SEIZURE RECURRENCE AFTER WITHDRAWAL OF ANTIEPILEPTIC DRUGS IN PATIENTS WITH NEUROCYSTICERCOSIS [J].
DELBRUTTO, OH .
NEUROLOGY, 1994, 44 (09) :1706-1709
[4]   Epidemiology of Taenia solium taeniasis and cysticercosis in two rural Guatemalan communities [J].
GarciaNoval, J ;
Allan, JC ;
Fletes, C ;
Moreno, E ;
DeMata, F ;
TorresAlvarez, R ;
DeAlfaro, HS ;
Yurrita, P ;
HiguerosMorales, H ;
Mencos, F ;
Craig, PS .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1996, 55 (03) :282-289
[5]   Neuroimaging abnormalities in Indian patients with uncontrolled partial seizures [J].
Garg, RK ;
Karak, B ;
Kar, AM .
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 1998, 7 (06) :497-500
[6]   Magnetisation transfer magnetic resonance imaging demonstration of perilesional gliosis - relation with epilepsy in treated or healed neurocysticercosis [J].
Gupta, RK ;
Kathuria, MK ;
Pradhan, S .
LANCET, 1999, 354 (9172) :44-45
[7]  
Henneberg R., 1912, HDB NEUROLOGIE, P643
[8]   RECENT ADVANCES IN THE DIAGNOSIS AND TREATMENT OF CEREBRAL CYSTICERCOSIS [J].
NASH, TE ;
NEVA, FA .
NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (23) :1492-1496
[9]   Edema associated with calcified lesions in neurocysticercosis [J].
Nash, TE ;
Patronas, NJ .
NEUROLOGY, 1999, 53 (04) :777-781
[10]  
NASH TN, 1997, DEFENSE BRAIN, P205