Defective auditory interhemispheric transfer in a patient with a PAX6 mutation

被引：13

作者：

Bamiou, DE

Musiek, FE

Sisodiya, SM

Free, SL

Mitchell, TN

Davies, RA

机构：

[1] Natl Hosp Neurol & Neurosurg, Dept Neurootol, London WC1N 3BG, England

[2] Univ Connecticut, DCP Commun Ctr, Storrs, CT USA

[3] UCL Inst Neurol, Dept Clin & Expt Epilepsy, London, England

来源：

NEUROLOGY | 2004年 / 62卷 / 03期

关键词：

D O I：

10.1212/01.WNL.0000106950.74155.0A

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Heterozygous PAX6 mutation is associated with an absent or hypoplastic anterior commissure and a reduction in the area of the corpus callosum. The authors found deficient auditory interhemispheric transfer in a 53-year-old woman with a PAX6 mutation who had an absent anterior commissure but normal callosal volume.

引用

收藏

页码：489 / 490

页数：2

相关论文

共 10 条

[1] MECHANISMS OF INTERHEMISPHERIC-TRANSFER AND PATTERNS OF COGNITIVE FUNCTION IN ACALLOSAL PATIENTS OF NORMAL INTELLIGENCE [J].

FISCHER, M ;

RYAN, SB ;

DOBYNS, WB .

ARCHIVES OF NEUROLOGY, 1992, 49 (03) :271-277

[2] Does "callosal relay'' explain ear advantage in dichotic monitoring? [J].

Jäncke, L .

LATERALITY, 2002, 7 (04) :309-320

[3] DICHOTIC-LISTENING, EVENT-RELATED POTENTIALS, AND INTERHEMISPHERIC-TRANSFER IN THE ELDERLY [J].

JERGER, J ;

ALFORD, B ;

LEW, H ;

RIVERA, V ;

CHMIEL, R .

EAR AND HEARING, 1995, 16 (05) :482-498

[4]

Jones L, 2002, DEVELOPMENT, V129, P5041

[5] Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies [J].

Lessard, N ;

Lepore, F ;

Villemagne, J ;

Lassonde, M .

BRAIN, 2002, 125 :1039-1053

[6]

MUSIEK FE, 1986, 2 HEMISPHERES 1 BRAI

[7]

PANDYA DN, 1986, 3 HEMISPHERES 1 BRAI

[8] The functional significance of perinatal corpus callosum damage: an fMRI study in young adults [J].

Santhouse, A. M. ;

ffytche, D. H. ;

Howard, R. J. ;

Williams, S. C. R. ;

Stewart, A. L. ;

Rooney, M. ;

Wyatt, J. S. ;

Rifkin, L. ;

Murray, R. M. .

BRAIN, 2002, 125 :1782-1792

[9] PAX6 haploinsufficiency causes cerebral malformation and olfactory dysfunction in humans [J].

Sisodiya, SM ;

Free, SL ;

Williamson, KA ;

Mitchell, TN ;

Willis, C ;

Stevens, JM ;

Kendall, BE ;

Shorvon, SD ;

Hanson, IM ;

Moore, AT ;

van Heyningen, V .

NATURE GENETICS, 2001, 28 (03) :214-216

[10]

ZAIDEL E, 1986, 2 HEMISPHERES 1 BRAI