Eight calves cloned from somatic cells of a single adult

被引：783

作者：

Kato, Y

Tani, T

Sotomaru, Y

Kurokawa, K

Kato, JY

Doguchi, H

Yasue, H

Tsunoda, Y

机构：

[1] Kinki Univ, Coll Agr, Lab Anim Reprod, Nara 6318505, Japan

[2] Kinki Univ, Res Inst Anim Dev Biotechnol, Nara 6318505, Japan

[3] Minist Agr Forestry & Fisheries, Natl Inst Anim Ind, Dept Anim Breeding & Genet, Tsukuba, Ibaraki 3050901, Japan

来源：

SCIENCE | 1998年 / 282卷 / 5396期

关键词：

D O I：

10.1126/science.282.5396.2095

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Eight carves were derived from differentiated cells of a single adult cow, five from cumulus cells and three from oviductal cells out of 10 embryos transferred to surrogate cows (80 percent success). ALL carves were visibly normal, but four died at or soon after birth from environmental causes, and postmortem analysis revealed no abnormality. These results show that bovine cumulus and oviductal epithelial cells of the adult have the genetic content to direct the development of newborn carves.

引用

页码：2095 / 2098

页数：4

共 15 条

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