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Takanawaenes, novel antifungal antibiotics produced by Streptomyces sp. K99-5278 -: I.: Taxonomy, fermentation, isolation and biological properties

被引：17
作者：
Kim, YP
Tomoda, H
Iizima, K
Fukuda, T
Matsumoto, A
Takahashi, Y
Ömura, S
机构：
[1] Kitasato Univ, Kitasato Inst Life Sci, Minato Ku, Tokyo 1088641, Japan
[2] Kitasato Inst, Minato Ku, Tokyo 1088641, Japan
来源：
JOURNAL OF ANTIBIOTICS | 2003年 / 56卷 / 05期
关键词：
D O I：
10.7164/antibiotics.56.448
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Three new pentaene macrolides having a 28-membered ring, designated takanawaenes A, B and C, were isolated from the fermentation broth of Streptomyces sp. K99-5278 by solvent extraction, silica-gel column chromatography and HPLC. Takanawaenes showed antifungal activity against Aspergillus niger, Mucor racemosus, Candida albicans and Saccharomyces cerevisiae.
引用
收藏
页码：448 / 453
页数：6
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