Layer-by-layer assembly of human serum albumin and phospholipid nanotubes based on a template

被引：78

作者：

Lu, G ^{[1
]}

Al, SF ^{[1
]}

Li, JB ^{[1
]}

机构：

[1] Chinese Acad Sci, Int Joint Lab, Ctr Mol Sci, Inst Chem,Key Lab Colloid & Interface Sci, Beijing 100080, Peoples R China

来源：

LANGMUIR | 2005年 / 21卷 / 05期

关键词：

D O I：

10.1021/la047771r

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The preparation of nanotubes from human serum albumin (HSA) and mixtures Of L-a-dimyristoylphosphatidic acid (DMPA)/HSA is described. The nanotubes were prepared via alternate adsorption of HSA of different/opposite charges (by variation of the pH) or by sequential adsorption of DMPA and HSA, respectively, onto the inner surfaces of porous anodic alumina templates. This simple layer-by-layer assembly results in a monodisperse size distribution and a uniform orientation. The nanotubes allow the specific incorporation of lipophilic components such as channels or receptors and may thus serve as probes or sensors for biological systems.

引用

页码：1679 / 1682

页数：4

共 34 条

[1] Highly flexible polyelectrolyte nanotubes [J].