Caffeine withdrawal in normal school-age children

被引:36
作者
Bernstein, GA
Carroll, ME
Dean, NW
Crosby, RD
Perwien, AR
Benowitz, NL
机构
[1] Univ Minnesota, Sch Med, Div Child & Adolescent Psychiat, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Sch Med, Dept Psychiat, Minneapolis, MN 55455 USA
[3] Neuropsychiat Res Inst, Fargo, ND USA
[4] Univ Florida, Dept Clin & Hlth Psychol, Gainesville, FL USA
[5] Univ Calif San Francisco, San Francisco, CA 94143 USA
关键词
caffeine; substance withdrawal syndrome; normal children;
D O I
10.1097/00004583-199808000-00016
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
Objective: Caffeine is widely consumed by children around the world. The purpose of this study was to determine whether children manliest withdrawal effects after cessation of caffeine intake. Method: Thirty normal children completed the single-blind, within-subjects, repeated-measures study with weekly sessions. Subjects were tested four times: (1) baseline ton regular caffeine diet); (2) on caffeine (approximately 120 to 145 mg/day); (3) during withdrawal (24 hours after discontinuation of caffeine taken for 13 consecutive days); and (4) at return to baseline. Subjects were evaluated with self-report measures of symptoms and objective measures of attention, motor performance, processing speed, and memory, Results: During caffeine withdrawal, there was a significant deterioration on response time of a visual continuous performance test of attention. This finding is consistent with caffeine withdrawal. The deterioration in response time appeared to persist for 1 week. Conclusions: Twenty-four hours after children discontinued caffeine, there was a decrease in performance an reaction time of a task requiring sustained attention. Further work is indicated to determine whether children manifest caffeine withdrawal effects after cessation of caffeine intake.
引用
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页码:858 / 865
页数:8
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