The effects of exercise on cognition and gait in Parkinson's disease: A scoping review

被引:47
作者
Intzandt, Brittany [1 ]
Beck, Eric N. [2 ]
Silveira, Carolina R. A. [3 ]
机构
[1] Concordia Univ, PERFORM Ctr, 7200 Rue Sherbrooke O, Montreal, PQ H4B 1R6, Canada
[2] Univ Dublin, Sch Med, Trinity Coll Dublin, Dublin 2, Ireland
[3] Lawson Hlth Res Inst, 750 Base Line Rd E, London, ON N6C 2R5, Canada
关键词
Parkinson's disease; Exercise; Gait; Cognition; Mobility; Aerobic training; Resistance training; Goal-based training; Executive function; Dual task; RANDOMIZED CONTROLLED-TRIAL; REDUCE FALL RISK; AEROBIC EXERCISE; BASAL GANGLIA; VIRTUAL-REALITY; WORKING-MEMORY; OLDER-ADULTS; EXECUTIVE FUNCTIONS; BRAIN ACTIVATION; MOTOR SEQUENCE;
D O I
10.1016/j.neubiorev.2018.09.018
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
010107 [宗教学]; 030301 [社会学]; 070906 [古生物学及地层学(含古人类学)];
摘要
Cognitive and gait deficits are two debilitating symptoms that occur in Parkinson's disease (PD). Importantly, a relationship between cognitive and gait deficits exists in PD, suggesting reliance on cognition is increased to compensate for gait deficits and/or deterioration of cognition and gait may share common mechanisms. Rehabilitation strategies targeting one factor could lead to the improvement of the other, presenting a unique opportunity to treat both simultaneously. Gold-standard pharmaceuticals partially alleviate these deficits with significant side effects, highlighting the importance of investigating adjunct therapies like exercise. We critically reviewed the influence of three exercise modalities (aerobic, resistance, and goal-based) on cognition and/or gait in PD. Most studies showed improvements in cognition or gait, yet, a limited number investigated them concurrently. This is the first review examining exercise for cognition and gait in PD. Key gaps in the literature are identified; potential exercise-driven mechanisms for enhancements in cognition and gait proposed, and suggestions for the design of future studies investigating the effects of exercise on cognition and gait in PD.
引用
收藏
页码:136 / 169
页数:34
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