Decremental response of the nasalis and hypothenar muscles in myasthenia gravis

被引：20

作者：

Niks, EH ^{[1
]}

Badrising, UA ^{[1
]}

Verschuuren, JJ ^{[1
]}

van Dijk, JG ^{[1
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Neurol & Clin Neurophysiol, NL-2300 RC Leiden, Netherlands

来源：

MUSCLE & NERVE | 2003年 / 28卷 / 02期

关键词：

myasthenia gravis; nasalis muscle; neuromuscular junction; neuoromuscular transmission defect; repetitive nerve stimulation;

D O I：

10.1002/mus.10411

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Repetitive nerve stimulation (RNS) is a standard diagnostic procedure in myasthenia gravis (MG). Although RNS sensitivity is highest in weak muscles, RNS is easier to perform in distal muscles that are often not affected. Twenty-five patients with MG were assessed to compare the sensitivity of RNS of the nasalis muscle to that of the hypothenar muscles. Abnormal decrement was found in hypothenar muscles in 9 patients (36%) and in the nasalis muscle in 13 patients (52%). RNS of the nasalis muscle appeared more useful to detect abnormal neuromuscular transmission in patients with oculobulbar MG (5 of 5) than hypothenar RNS (1 of 5). In patients with generalized MG, hypothenar muscles had a similar yield of abnormal RNS tests.

引用

页码：236 / 238

页数：3

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