Cell biology - Chewing the fat - ACC and energy balance

被引:23
作者
Ruderman, N [1 ]
Flier, JS
机构
[1] BioSquare 2, Diabet Unit, Boston, MA 02118 USA
[2] Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA
关键词
D O I
10.1126/science.1060277
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:2558 / 2559
页数:2
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共 12 条
[1]   Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver [J].
Abel, ED ;
Peroni, O ;
Kim, JK ;
Kim, YB ;
Boss, O ;
Hadro, E ;
Minnemann, T ;
Shulman, GI ;
Kahn, BB .
NATURE, 2001, 409 (6821) :729-733
[2]   The subcellular localization of acetyl-CoA carboxylase 2 [J].
Abu-Elheiga, L ;
Brinkley, WR ;
Zhong, L ;
Chirala, SS ;
Woldegiorgis, G ;
Wakil, SJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (04) :1444-1449
[3]   Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2 [J].
Abu-Elheiga, L ;
Matzuk, MM ;
Abo-Hashema, KAH ;
Wakil, SJ .
SCIENCE, 2001, 291 (5513) :2613-2616
[4]   Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean [J].
Clapham, JC ;
Arch, JRS ;
Chapman, H ;
Haynes, A ;
Lister, C ;
Moore, GBT ;
Piercy, V ;
Carter, SA ;
Lehner, I ;
Smith, SA ;
Beeley, LJ ;
Godden, RJ ;
Herrity, N ;
Skehel, M ;
Changani, KK ;
Hockings, PD ;
Reid, DG ;
Squires, SM ;
Hatcher, J ;
Trail, B ;
Latcham, J ;
Rastan, S ;
Harper, AJ ;
Cadenas, S ;
Buckingham, JA ;
Brand, MD ;
Abuin, A .
NATURE, 2000, 406 (6794) :415-418
[5]   Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice [J].
Fruebis, J ;
Tsao, TS ;
Javorschi, S ;
Ebbets-Reed, D ;
Erickson, MRS ;
Yen, FT ;
Bihain, BE ;
Lodish, HF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (04) :2005-2010
[6]   Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors [J].
Loftus, TM ;
Jaworsky, DE ;
Frehywot, GL ;
Townsend, CA ;
Ronnett, GV ;
Lane, MD ;
Kuhajda, FP .
SCIENCE, 2000, 288 (5475) :2379-2381
[7]   Towards a molecular understanding of adaptive thermogenesis [J].
Lowell, BB ;
Spiegelman, BM .
NATURE, 2000, 404 (6778) :652-660
[8]   The mitochondrial carnitine palmitoyltransferase system - From concept to molecular analysis [J].
McGarry, JD ;
Brown, NF .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 244 (01) :1-14
[9]   Malonyl-CoA, fuel sensing, and insulin resistance [J].
Ruderman, NB ;
Saha, AK ;
Vavvas, D ;
Witters, LA .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 1999, 276 (01) :E1-E18
[10]   Obesity and the regulation of energy balance [J].
Spiegelman, BM ;
Flier, JS .
CELL, 2001, 104 (04) :531-543