Transjugular intrahepatic portosystemic shunt is a nonsurgical procedure used to manage the complications of portal hypertension. This report describes three cases of fluoroscopy-induced radiodermatitis after transjugular intrahepatic portosystemic shunt and reviews the characteristics and treatment of radiation-induced skin reactions. (Am J Gastroenterol 1998;93:1546-1549. (C) 1998 by Am. Coll. of Gastroenterology).