Activation of B-raf in non-malignant nevi predicts a novel tumor suppressor gene in melanoma (MAP kinase phosphatase)

被引：9

作者：

Arbiser, JL ^{[1
]}

机构：

[1] Emory Univ, Sch Med, Dept Dermatol, Atlanta, GA 30322 USA

[2] Emory Univ, Sch Med, Emory Skin Dis Res Core Ctr, Atlanta, GA USA

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2003年 / 121卷 / 05期

关键词：

D O I：

10.1046/j.1523-1747.2003.12583.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

[No abstract available]

引用

页码：XIV / XIV

页数：1

共 9 条

[1] Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features [J].

Bastian, BC ;

LeBoit, PE ;

Pinkel, D .

AMERICAN JOURNAL OF PATHOLOGY, 2000, 157 (03) :967-972

[2]

Cohen C, 2002, CLIN CANCER RES, V8, P3728

[3] Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells [J].

Conner, SR ;

Scott, G ;

Aplin, AE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (36) :34548-34554

[4] Mutations of the BRAF gene in human cancer [J].

Davies, H ;

Bignell, GR ;

Cox, C ;

Stephens, P ;

Edkins, S ;

Clegg, S ;

Teague, J ;

Woffendin, H ;

Garnett, MJ ;

Bottomley, W ;

Davis, N ;

Dicks, N ;

Ewing, R ;

Floyd, Y ;

Gray, K ;

Hall, S ;

Hawes, R ;

Hughes, J ;

Kosmidou, V ;

Menzies, A ;

Mould, C ;

Parker, A ;

Stevens, C ;

Watt, S ;

Hooper, S ;

Wilson, R ;

Jayatilake, H ;

Gusterson, BA ;

Cooper, C ;

Shipley, J ;

Hargrave, D ;

Pritchard-Jones, K ;

Maitland, N ;

Chenevix-Trench, G ;

Riggins, GJ ;

Bigner, DD ;

Palmieri, G ;

Cossu, A ;

Flanagan, A ;

Nicholson, A ;

Ho, JWC ;

Leung, SY ;

Yuen, ST ;

Weber, BL ;

Siegler, HF ;

Darrow, TL ;

Paterson, H ;

Marais, R ;

Marshall, CJ ;

Wooster, R .

NATURE, 2002, 417 (6892) :949-954

[5] Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling [J].

Govindarajan, B ;

Bai, XH ;

Cohen, C ;

Zhong, H ;

Kilroy, S ;

Louis, G ;

Moses, M ;

Arbiser, JL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (11) :9790-9795

[6] Molecular genetics of familial cutaneous melanoma [J].

Haluska, FG ;

Hodi, FS .

JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (02) :670-682

[7] High frequency of BRAF mutations in nevi [J].

Pollock, PM ;

Harper, UL ;

Hansen, KS ;

Yudt, LM ;

Stark, M ;

Robbins, CM ;

Moses, TY ;

Hostetter, G ;

Wagner, U ;

Kakareka, J ;

Salem, G ;

Pohida, T ;

Heenan, P ;

Duray, P ;

Kallioniemi, O ;

Hayward, NK ;

Trent, JM ;

Meltzer, PS .

NATURE GENETICS, 2003, 33 (01) :19-20

[8]

Sviderskaya EV, 2002, JNCI-J NATL CANCER I, V94, P446

[9] Mutations of the BRAF gene in benign and malignant melanocytic lesions [J].

Yazdi, AS ;

Palmedo, G ;

Flaig, MJ ;

Puchta, U ;

Reckwerth, A ;

Rütten, A ;

Mentzel, T ;

Hügel, H ;

Hantschke, M ;

Schmid-Wendtner, MH ;

Kutzner, H ;

Sander, CA .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2003, 121 (05) :1160-1162

← 1 →