Synthesis of novel C7-aryl substituted pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) via pro-N10-Troc protection and Suzuki coupling

被引：7

作者：

Guiotto, A

Howard, PW

Baraldi, PG

Thurston, DE

机构：

[1] Portsmouth Polytech, Sch Pharm & Biomed Sci, CRC, Gene Targeted Drug Design Res Grp, Portsmouth PO1 2DT, Hants, England

[2] Univ Ferrara, Dipartimento Sci Farmaceut, I-44100 Ferrara, Italy

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 21期

关键词：

D O I：

10.1016/S0960-894X(97)10083-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Novel C7-aryl pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) have been synthesized via Suzuki coupling between a 7-Iodo N10-Troc-protected PBD carbinolamine and commercially available boronic acids, (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3017 / 3018

页数：2

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