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A census of carbohydrate-active enzymes in the genome of Arabidopsis thaliana
被引:192
作者:
Henrissat, B
Coutinho, PM
Davies, GJ
机构:
[1] CNRS, UMR 6098, F-13402 Marseille 20, France
[2] Univ Aix Marseille I & II, F-13402 Marseille 20, France
[3] Inst Super Tecn, Ctr Biol & Chem Engn, P-1049001 Lisbon, Portugal
[4] Univ York, Dept Chem, Struct Biol Lab, York Y010 5DD, N Yorkshire, England
基金:
英国生物技术与生命科学研究理事会;
英国惠康基金;
关键词:
Arabidopsis;
genome;
glycoside hydrolases;
glycosyltransferases;
D O I:
10.1023/A:1010667012056
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The synthesis, modification, and breakdown of carbohydrates is one of the most fundamentally important reactions in nature. The structural and functional diversity of glycosides is mirrored by a vast array of enzymes involved in their synthesis (glycosyltransferases), modification (carbohydrate esterases) and breakdown (glycoside hydrolases and polysaccharide lyases). The importance of these processes is reflected in the dedication of 1-2% of an organism's genes to glycoside hydrolases and glycosyltransferases alone. In plants, these processes are of particular importance for cell-wall synthesis and expansion, starch metabolism, defence against pathogens, symbiosis and signalling. Here we present an analysis of over 730 open reading frames representing the two main classes of carbohydrate-active enzymes, glycoside hydrolases and glycosyltransferases, in the genome of Arabidopsis thaliana. The vast importance of these enzymes in cell-wall formation and degradation is revealed along with the unexpected dominance of pectin degradation in Arabidopsis, with at least 170 open-reading frames dedicated solely to this task.
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页码:55 / 72
页数:18
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