Impact of thalamic deep brain stimulation on disability and health-related quality of life in patients with essential tremor

被引:65
作者
Hariz, GM
Lindberg, M
Bergenheim, AT [1 ]
机构
[1] Univ Hosp No Sweden, Dept Clin Neurosci, S-90185 Umea, Sweden
[2] Umea Univ, Sect Occupat Therapy, Dept Community Med & Rehabil, S-90187 Umea, Sweden
关键词
D O I
10.1136/jnnp.72.1.47
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objectives: To evaluate the impact of thalamic deep brain stimulation (DBS) on disability and health-related quality of life in patients with essential tremor. Methods: Twenty seven consecutive patients were evaluated prospectively, before surgery and at a mean of 12 months (range 6-26) after thalamic DBS. Assessment tools included the Fahn-Tolosa-Marin tremor rating scale (TRS), activities of daily living (ADL) taxonomy, Nottingham health profile (NHP) and the visual analogue scale (VAS) for measuring impact of disease on life. Additional information on the side effects of, and expectations from surgery was obtained by interview. Results: Thalamic DBS improved the ability of the patients in eating, drinking, writing, home maintenance, hobbies, and participation in society. Activities of daily life requiring bimanual skills were less improved. The emotional condition of the patients was positively affected and the negative impact the disease on life as a whole, and on social life was decreased. Seventy per cent of the patients considered that the surgical treatment met their expectations. Conclusions: After thalamic DBS, health-related quality of life including disability in ADL and social life were improved in patients with essential tremor.
引用
收藏
页码:47 / 52
页数:6
相关论文
共 34 条
[1]  
AUFF E, 1991, J NEURAL TRANSM-GEN, P105
[2]   Chronic electrical stimulation of the ventralis intermedius nucleus of the thalamus as a treatment of movement disorders [J].
Benabid, AL ;
Pollak, P ;
Gao, DM ;
Hoffmann, D ;
Limousin, P ;
Gay, E ;
Payen, I ;
Benazzouz, A .
JOURNAL OF NEUROSURGERY, 1996, 84 (02) :203-214
[3]   LONG-TERM SUPPRESSION OF TREMOR BY CHRONIC STIMULATION OF THE VENTRAL INTERMEDIATE THALAMIC NUCLEUS [J].
BENABID, AL ;
POLLAK, P ;
GERVASON, C ;
HOFFMANN, D ;
GAO, DM ;
HOMMEL, M ;
PERRET, JE ;
DEROUGEMONT, J .
LANCET, 1991, 337 (8738) :403-406
[4]  
BENABID AL, 1993, ACTA NEUROCHIR, P39
[5]   CONTROL OF TREMOR AND INVOLUNTARY MOVEMENT-DISORDERS BY CHRONIC STEREOTAXIC STIMULATION OF THE VENTRAL INTERMEDIATE THALAMIC NUCLEUS [J].
BLOND, S ;
CAPARROSLEFEBVRE, D ;
PARKER, F ;
ASSAKER, R ;
PETIT, H ;
GUIEU, JD ;
CHRISTIAENS, JL .
JOURNAL OF NEUROSURGERY, 1992, 77 (01) :62-68
[6]   IS ESSENTIAL TREMOR BENIGN [J].
BUSENBARK, KL ;
NASH, J ;
NASH, S ;
HUBBLE, JP ;
KOLLER, WC .
NEUROLOGY, 1991, 41 (12) :1982-1983
[7]  
Clarke PRF, 1964, B BRIT PSYCHOL SOC, V17, p18A
[8]   CLINICAL MANIFESTATIONS OF ESSENTIAL TREMOR [J].
CRITCHLEY, E .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1972, 35 (03) :365-+
[9]  
Fahn S., 1988, PARKINSONS DIS MOVEM, P225
[10]   Outcome of unilateral and bilateral pallidotomy for Parkinson's disease: Patient assessment [J].
Favre, J ;
Burchiel, KJ ;
Taha, JM ;
Hammerstad, J .
NEUROSURGERY, 2000, 46 (02) :344-353