VIRAL LOAD AND ACUTE OTITIS MEDIA DEVELOPMENT AFTER HUMAN METAPNEUMOVIRUS UPPER RESPIRATORY TRACT INFECTION

被引：18

作者：

Nokso-Koivisto, Johanna ^{[1
]}

Pyles, Richard B. ^{[1
,2
]}

Miller, Aaron L. ^{[1
]}

Patel, Janak A. ^{[1
]}

Loeffelholz, Michael ^{[3
]}

Chonmaitree, Tasnee ^{[1
,3
]}

机构：

[1] Univ Texas Med Branch, Dept Pediat, Galveston, TX 77555 USA

[2] Univ Texas Med Branch, Dept Microbiol & Immunol, Galveston, TX 77555 USA

[3] Univ Texas Med Branch, Dept Pathol, Galveston, TX 77555 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2012年 / 31卷 / 07期

基金：

美国国家卫生研究院;

关键词：

human metapneumovirus; upper respiratory tract infection; acute otitis media; viral load; YOUNG-CHILDREN; SYNCYTIAL VIRUS; DISEASE; ASSOCIATION; DIAGNOSIS; SYMPTOMS;

D O I：

10.1097/INF.0b013e3182539d92

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The role of human metapneumovirus (hMPV) in acute otitis media complicating upper respiratory tract infection (URI) was studied. Nasopharyngeal specimens from 700 URI episodes in 200 children were evaluated; 47 (7%) were positive for hMPV, 25 (3.6%) with hMPV as the only virus. Overall, 24% of URI episodes with hMPV only were complicated by acute otitis media, which was the lowest rate compared with other respiratory viruses. hMPV viral load was significantly higher in children with fever, but there was no difference in viral load in children with hMPV-positive URI with or without acute otitis media complication.

引用

页码：763 / 766

页数：4

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