Effect of cigarette smoking on prepulse inhibition of the acoustic startle reflex in healthy male smokers

被引：106

作者：

Kumari, V

Checkley, SA

Gray, JA

机构：

[1] Institute of Psychiatry, University of London, London SE5 8AF, De Crespigny Park

来源：

PSYCHOPHARMACOLOGY | 1996年 / 128卷 / 01期

基金：

英国惠康基金;

关键词：

prepulse inhibition; acoustic startle reflex; cigarette smoking; nicotine;

D O I：

10.1007/s002130050109

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The present study investigated the effects of cigarette smoking on prepulse inhibition (PPI) of the acoustic startle reflex in healthy men. Cigarette smoking in a group of overnight smoking-deprived smokers increased PPI as compared to the smoking-deprived condition. This finding is consistent with previous animal studies showing that nicotine increases PPI of the acoustic startle reflex. In addition, cigarette smoking also reduced startle amplitude during the first 6-7 min of the post-smoking session.

引用

页码：54 / 60

页数：7

共 51 条

[1] NICOTINE INCREASES SENSORY GATING MEASURED AS INHIBITION OF THE ACOUSTIC STARTLE REFLEX IN RATS [J].