[Ir(cod)Cl]2/FDPPE-catalyzed chemo- and regioselective cyclotrimerization of two different terminal alkynes to give 1,3,5-trisubstituted benzenes

被引：21

作者：

Onodera, Gen ^{[1
]}

Matsuzawa, Masayoshi ^{[1
]}

Aizawa, Takahiro ^{[1
]}

Kitahara, Takeshi ^{[1
]}

Shimizu, Yoshihisa ^{[1
]}

Kezuka, Satoko ^{[1
]}

Takeuchi, Ryo ^{[1
]}

机构：

[1] Aoyama Gakuin Univ, Dept Chem & Biol Sci, Sagamihara, Kanagawa 2298558, Japan

来源：

SYNLETT | 2008年 / 05期

关键词：

iridium; cyclotrimerization; regioselectivity; alkynes; catalysis;

D O I：

10.1055/s-2008-1042810

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[Ir(cod)Cl](2) in combination with 1,2-bis(dipentafluorophenylphosphino)ethane catalyzes chemo- and regioselective cyclotrimerization of two different alkynes. The reaction of methyl propiolate with I-hexyne gave methyl 3,5-di(n-butyl)benzoate as a single product in 88% yield.

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收藏

页码：755 / 758

页数：4

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