Improved synthesis of γ-nitro-α-amino ester and acid derivatives

被引：8

作者：

Ballini, R

Balsamini, C

Bartoccini, F

Gianotti, M

Martinelli, C

Savoretti, N

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, MC, Italy

[2] Univ Urbino, Ist Chim Farmaceut, I-61029 Urbino, PU, Italy

来源：

SYNTHESIS-STUTTGART | 2005年 / 02期

关键词：

microwave-assisted synthesis; alpha-amino acids; methyl N-(diphenylmethylene)-2,3-didehydroalaninate; nitroalkanes;

D O I：

10.1055/s-2004-834927

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A useful microwave-assisted synthesis of gamma-nitro-alpha-amino esters and corresponding acids, under mild conditions and without solvent, is described. The desired products were obtained via Michael addition from methyl N-(diphenylmethylene)-2,3-didehydroalaninate and commercially available nitroalkanes.

引用

页码：296 / 300

页数：5

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