An efficient and highly selective cleavage of N-tert-butoxycarbonyl group under microwave irradiation

被引：17

作者：

Bose, DS ^{[1
]}

Lakshminarayana, V ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem 3, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 31期

关键词：

microwave irradiation; tert-butylcarbamate; Lewis acid catalyst; chemoselectivity;

D O I：

10.1016/S0040-4039(98)01094-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and high yielding method for the cleavage of t-Boc carbamates is described which occurs under mild and solvent-free conditions using microwave irradiation. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：5631 / 5634

页数：4

共 10 条

[1] CATECHOL BORON HALIDES - MILD AND SELECTIVE REAGENTS FOR CLEAVAGE OF COMMON PROTECTING GROUPS [J].

BOECKMAN, RK ;

POTENZA, JC .

TETRAHEDRON LETTERS, 1985, 26 (11) :1411-1414

[2] MICROWAVE-ASSISTED ORGANIC-REACTIONS [J].

CADDICK, S .

TETRAHEDRON, 1995, 51 (38) :10403-10432

[3]

Clark J.H., 1994, CATALYSIS ORGANIC RE

[4]

Hwu JR, 1996, TETRAHEDRON LETT, V37, P2035

[5]

KOCIENSKI PJ, 1994, PROTECTING GROUPS, P185

[6]

PAQUETTE LA, 1995, ENCY REAGENTS ORGANI, P156

[7] ZWEI SYNTHESEN DES ALPHA-MELANOTROPINS (ALPHA-MSH) MIT HILFE LEICHT ENTFERNBARER SCHUTZGRUPPEN [J].

SCHWYZER, R ;

COSTOPANAGIOTIS, A ;

SIEBER, P .

HELVETICA CHIMICA ACTA, 1963, 46 (03) :870-+

[8]

Smith K., 1992, SOLID SUPPORTS CATAL

[9] Solid state deoximation with ammonium persulfate-silica gel: Regeneration of carbonyl compounds using microwaves [J].

Varma, RS ;

Meshram, HM .

TETRAHEDRON LETTERS, 1997, 38 (31) :5427-5428

[10] TOTAL SYNTHESIS OF (+/-)-CHAENORHINE [J].

WASSERMAN, HH ;

ROBINSON, RP ;

CARTER, CG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (06) :1697-1698

← 1 →