Potential Biomarkers

被引：21

作者：

Spiller, Robin C. ^{[1
]}

机构：

[1] Univ Nottingham Hosp, NIHR Biomed Res Unit, Nottingham Digest Dis Ctr, Nottingham NG7 2UH, England

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2011年 / 40卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Biomarkers; Irritable bowel syndrome; Diagnosis; IRRITABLE-BOWEL-SYNDROME; KAPPA-OPIOID AGONIST; CHLORIDE CHANNEL ACTIVATOR; TACHYKININ NK2 RECEPTORS; COLONIC TRANSIT; GASTROINTESTINAL TRANSIT; DIARRHEA-PREDOMINANT; CLINICAL-TRIAL; HEALTHY-VOLUNTEERS; IMMUNE ACTIVATION;

D O I：

10.1016/j.gtc.2011.01.001

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A "biomarker" (biological marker) is an indicator of a bodily function that can be objectively measured. A wide range of possible biomarkers for IBS have been considered but at present only gut transit measured using radio-isotope markers meet the criteria of reproducibility and availability. While barostat studies perform reasonably in expert centers, to do them reproducibly requires considerable effort and standardization. This makes them unsuitable for widespread use. However radio-isotope tests are expensive and of limited availability so the search for other more convenient markers including blood and stool tests is still an important goal for the future.

引用

收藏

页码：121 / +

页数：21

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