c-erbB-4/HER4: friend or foe?

被引：49

作者：

Gullick, WJ ^{[1
]}

机构：

[1] Univ Kent, Canc Biol Lab, Res Sch Biosci, Canterbury CT2 7NJ, Kent, England

来源：

JOURNAL OF PATHOLOGY | 2003年 / 200卷 / 03期

关键词：

growth factor; growth factor receptor; tyrosine kinase inhibition; signal transduction; breast cancer;

D O I：

10.1002/path.1335

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

The c-erbB-4 receptor has ligand stimulated tyrosine kinase activity but reports differ as to whether it induces cell division or differentiation. There is also controversy regarding its role in breast cancer, with some reports associating overexpression with short survival and others with longer life. Copyright (C) 2003 John Wiley Sons, Ltd.

引用

页码：279 / 281

页数：3

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