Close encounters: regulation of vertebrate skeletal myogenesis by cell-cell contact

被引:130
作者
Krauss, RS [1 ]
Cole, F [1 ]
Gaio, U [1 ]
Takaesu, G [1 ]
Zhang, W [1 ]
Kang, JS [1 ]
机构
[1] Mt Sinai Sch Med, Brookdale Dept Mol Cell & Dev Biol, New York, NY 10029 USA
关键词
muscle development; cell adhesion; cell differention; signal transduction; cadherin; immunoglobulin superfamily;
D O I
10.1242/jcs.02397
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Cells of the vertebrate skeletal muscle lineage develop in a highly ordered process that includes specification, migration and differentiation into multinucleated myofibers. The changes in gene expression and cell morphology that occur during myogenic differentiation must be coordinated with each other in a spatiotemporal fashion; one way that this might occur is through regulation of these processes by cell-cell adhesion and resultant signaling. The past several years have witnessed the identification of molecules that are likely to be mediators of the promyogenic effects of cell-cell contact and some of the mechanisms by which they work. These include: the community factor, embryonic fibroblast growth factor (eFGF); classical cadherins, which mediate both adhesion and signaling; and cadherin-associated immunoglobulin superfamily members such as CDO, BOC and neogenin. Genetic evidence for the promyogenic roles of some of these factors is emerging. In other cases, potential compensatory or redundant functions necessitate future construction of double or triple mutants. Mechanistic studies in vitro indicate that specific cadherins and immunoglobulin superfamily proteins exert some of their effects in an interdependent fashion by signaling from a multiprotein complex found at sites of cell-cell contact.
引用
收藏
页码:2355 / 2362
页数:8
相关论文
共 80 条
[1]   TARGETED INACTIVATION OF THE MUSCLE REGULATORY GENE MYF-5 RESULTS IN ABNORMAL RIB DEVELOPMENT AND PERINATAL DEATH [J].
BRAUN, T ;
RUDNICKI, MA ;
ARNOLD, HH ;
JAENISCH, R .
CELL, 1992, 71 (03) :369-382
[2]   Immunoglobulin superfamily receptors:: cis-interactions, intracellular adapters and alternative splicing regulate adhesion [J].
Brümmendorf, T ;
Lemmon, V .
CURRENT OPINION IN CELL BIOLOGY, 2001, 13 (05) :611-618
[3]   Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth cones [J].
Campbell, DS ;
Holt, CE .
NEURON, 2003, 37 (06) :939-952
[4]   Neural cell adhesion molecule (NCAM) and myoblast fusion [J].
Charlton, CA ;
Mohler, WA ;
Blau, HM .
DEVELOPMENTAL BIOLOGY, 2000, 221 (01) :112-119
[5]   Fusion competence of myoblasts rendered genetically null for N-cadherin in culture [J].
Charlton, CA ;
Mohler, WA ;
Radice, GL ;
Hynes, RO ;
Blau, HM .
JOURNAL OF CELL BIOLOGY, 1997, 138 (02) :331-336
[6]   N-cadherin-dependent cell-cell contact regulates Rho GTPases and β-catenin localization in mouse C2C12 myoblasts [J].
Charrasse, S ;
Meriane, M ;
Comunale, F ;
Blangy, A ;
Gauthier-Rouvière, C .
JOURNAL OF CELL BIOLOGY, 2002, 158 (05) :953-965
[7]   Towards a molecular pathway for myoblast fusion in Drosophila [J].
Chen, EH ;
Olson, EN .
TRENDS IN CELL BIOLOGY, 2004, 14 (08) :452-460
[8]  
CIFUENTESDIAZ C, 1994, DEVELOPMENT, V120, P1
[9]   Positive regulation of myogenic bHLH factors and skeletal muscle development by the cell surface receptor CDO [J].
Cole, F ;
Zhang, W ;
Geyra, A ;
Kang, JS ;
Krauss, RS .
DEVELOPMENTAL CELL, 2004, 7 (06) :843-854
[10]   Cadherin-mediated differential cell adhesion controls slow muscle cell migration in the developing zebrafish myotome [J].
Cortés, F ;
Daggett, D ;
Bryson-Richardson, RJ ;
Neyt, C ;
Maule, J ;
Gautier, P ;
Hollway, GE ;
Keenan, D ;
Currie, PD .
DEVELOPMENTAL CELL, 2003, 5 (06) :865-876