Site-specific control of distances between gold nanoparticles using phosphorothioate anchors on DNA and a short bifunctional molecular fastener

被引：85

作者：

Lee, Jung Heon ^{[1
,4
]}

Wernette, Daryl P. ^{[2
,4
]}

Yigit, Mehmet V. ^{[3
,4
]}

Liu, Juewen ^{[2
,4
]}

Wang, Zidong ^{[1
,4
]}

Lu, Yi ^{[1
,2
,3
,4
]}

机构：

[1] Univ Illinois, Dept Mat Sci & Engn, Urbana, IL 61801 USA

[2] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

[3] Univ Illinois, Ctr Biophys & Computat Biol, Urbana, IL 61801 USA

[4] Univ Illinois, Beckman Inst Adv Sci & Technol, Urbana, IL 61801 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 47期

关键词：

DNA; nanostructures; nanotechnology; self-assembly; surface chemistry;

D O I：

10.1002/anie.200702569

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Going for double gold: Precise control of the positions of and distances between gold nanoparticles (AuNP; gold spheres in picture) is achieved by linking the AuNPs to phosphorothioate-modified DNA (green and red helices) with a bifunctional fastener. The distance between AuNPs is controlled simply by changing the position of the modifications on the DNA template. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：9006 / 9010

页数：5

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