Effect of biomaterial surface morphologies on bone marrow cell performance

被引:10
作者
Bruinink, A
Kaiser, JP
Meyer, DC
机构
[1] Empa Mat Sci & Technol, Lab Biocompatible Mat, CH-9014 St Gallen, Switzerland
[2] Univ Zurich Uniklin, CH-8008 Zurich, Switzerland
关键词
D O I
10.1002/adem.200500065
中图分类号
T [工业技术];
学科分类号
08 [工学];
摘要
A set-up for implant surface optimization was developed with which large quantities of differently structured surfaces can be prepared which affect bone cell appearance and its biochemical characteristics. It was aimed to determine the type of positive microstructure which is able to affect the cells. Also, the extent to which cell morphology is predictive for cell functionality was assessed. It was found that all the surface microstructure tested were nearly positive in shape, i.e. protruding, including textile fabric-like structures.
引用
收藏
页码:411 / 418
页数:8
相关论文
共 45 条
[1]
Chemistry of polymer biodegradation and implications on parenteral drug delivery [J].
Acemoglu, M .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2004, 277 (1-2) :133-139
[2]
Boyan B. D., 2003, European Cells & Materials, V6, P22
[3]
Boyan BD, 1998, J BIOMED MATER RES, V39, P77, DOI 10.1002/(SICI)1097-4636(199801)39:1<77::AID-JBM10>3.0.CO
[4]
2-L
[5]
Pretreatment of bone with osteoclasts affects phenotypic expression of osteoblast-like cells [J].
Boyan, BD ;
Schwartz, Z ;
Lohmann, CH ;
Sylvia, VL ;
Cochran, DL ;
Dean, DD ;
Puzas, JE .
JOURNAL OF ORTHOPAEDIC RESEARCH, 2003, 21 (04) :638-647
[6]
Grooves affect primary bone marrow but not osteoblastic MC3T3-E1 cell cultures [J].
Bruinink, A ;
Wintermantel, E .
BIOMATERIALS, 2001, 22 (18) :2465-2473
[7]
Bruinink A., 1992, BRAIN BITS PIECES, P23
[8]
BRUNETTE DM, 1988, SURFACE CHARACTERIZA, P203
[9]
Chehroudi B, 1997, J BIOMED MATER RES, V34, P279
[10]
Topographical control of cells [J].
Curtis, A ;
Wilkinson, C .
BIOMATERIALS, 1997, 18 (24) :1573-1583