Rubella and pregnancy: diagnosis, management and outcomes

被引:79
作者
Bouthry, Elise [1 ]
Picone, Olivier [2 ,3 ]
Hamdi, Ghada [2 ]
Grangeot-Keros, Liliane [1 ]
Ayoubi, Jean-Marc [2 ]
Vauloup-Fellous, Christelle [1 ]
机构
[1] Univ Paris 11, Hop Paul Brousse, AP HP,UMR S 785,INSERM U785, Natl Reference Lab Matemofetal Rubella Infect,Lab, Villejuif, France
[2] Hop Foch, Serv Gynecol Obstet & Biol Reprod, Suresnes, France
[3] Univ Versailles St Quentin Yvelines, EA2493, UFR Sci Sante Simone Veil, Montigny Le Bretonneux, France
关键词
CONGENITAL-RUBELLA; E1; GLYCOPROTEIN; IMMUNE-RESPONSE; VIRUS; MEASLES; VACCINATION; PERSISTENCE; ANTIBODIES; INFECTION; WOMEN;
D O I
10.1002/pd.4467
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Rubella is a mild viral disease that typically occurs in childhood. Rubella infection during pregnancy causes congenital rubella syndrome, including the classic triad of cataracts, cardiac abnormalities and sensorineural deafness. Highly effective vaccines have been developed since 1969, and vaccination campaigns have been established in many countries. Although there has been progress, the prevention and diagnosis of rubella remain problematic. This article reviews the implications and management of rubella during pregnancy. (c) 2014 John Wiley & Sons, Ltd.
引用
收藏
页码:1246 / 1253
页数:8
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