Regioselective double Suzuki couplings of 4,5-dibromothiophene-2-carboxaldehyde

被引：27

作者：

Handy, Scott T. ^{[1
]}

Mayi, Diyar ^{[1
]}

机构：

[1] Middle Tennessee State Univ, Dept Chem, Murfreesboro, TN 37132 USA

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 46期

关键词：

regioselective; Suzuki coupling; thiophenes; one-pot; dehalogenation;

D O I：

10.1016/j.tetlet.2007.09.114

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conditions have been identified that enable the one-pot double Suzuki coupling of 4,5-dibromothiophene-2-carboxaldehyde to proceed in good yield. The key to success in these reactions is the use of minimal amounts of water to avoid significant amounts of dehalogenation during the first coupling. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：8108 / 8110

页数：3

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