The implications of hyperhomocysteinemia in a patient with type 1 diabetes

被引：4

作者：

van Leeuwen-Wintjens, HRAJB ^{[1
]}

Muls, EE ^{[1
]}

机构：

[1] Univ Hosp Gasthuisberg, Afd Endocrinol Metab & Voeding, B-3000 Louvain, Belgium

来源：

ACTA CLINICA BELGICA | 1998年 / 53卷 / 05期

关键词：

D O I：

10.1080/17843286.1998.11754188

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present a patient with type 1 diabetes mellitus, who had severe, progressive macrovascular disease despite an optimal control of modifiable risk factors. Screening for other risk factors revealed a markedly elevated plasma homocysteine level, that was secondary to pernicious anemia. The biological and clinical implications of this association are discussed.

引用

页码：349 / 352

页数：4

共 26 条

[1] LACK OF ASSOCIATION BETWEEN PLASMA HOMOCYSTEINE LEVELS AND MICROANGIOPATHY IN TYPE-1 DIABETES-MELLITUS
AGARDH, CD
AGARDH, E
ANDERSSON, A
HULTBERG, B
[J]. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1994, 54 (08) : 637 - 641
[2] PLASMA HOMOCYSTEINE CONCENTRATIONS IN JAPANESE PATIENTS WITH NON-INSULIN-DEPENDENT DIABETES-MELLITUS - EFFECT OF PARENTERAL METHYLCOBALAMIN TREATMENT
ARAKI, A
SAKO, Y
ITO, H
[J]. ATHEROSCLEROSIS, 1993, 103 (02) : 149 - 157
[3] Hyperhomocysteinemia in end-stage renal disease: Prevalence, etiology, and potential relationship to arteriosclerotic outcomes
Bostom, AG
Lathrop, L
[J]. KIDNEY INTERNATIONAL, 1997, 52 (01) : 10 - 20
[4] A QUANTITATIVE ASSESSMENT OF PLASMA HOMOCYSTEINE AS A RISK FACTOR FOR VASCULAR-DISEASE - PROBABLE BENEFITS OF INCREASING FOLIC-ACID INTAKES
BOUSHEY, CJ
BERESFORD, SAA
OMENN, GS
MOTULSKY, AG
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1995, 274 (13): : 1049 - 1057
[5] Vitamins as homocysteine-lowering agents
Brattstrom, L
[J]. JOURNAL OF NUTRITION, 1996, 126 (04) : S1276 - S1280
[6] HYPERHOMOCYSTEINEMIA - AN INDEPENDENT RISK FACTOR FOR VASCULAR-DISEASE
CLARKE, R
DALY, L
ROBINSON, K
NAUGHTEN, E
CAHALANE, S
FOWLER, B
GRAHAM, I
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (17) : 1149 - 1155
[7] COLWELL JA, 1996, DIABETES MELLITUS TH, P207
[8] IS HYPERHOMOCYSTEINAEMIA A RISK FACTOR FOR RECURRENT VENOUS THROMBOSIS
DENHEIJER, M
BLOM, HJ
GERRITS, WBJ
ROSENDAAL, FR
HAAK, HL
WIJERMANS, PW
BOS, GMJ
[J]. LANCET, 1995, 345 (8954): : 882 - 885
[9] HOMOCYSTEINE THIOLACTONE DISPOSAL BY HUMAN ARTERIAL ENDOTHELIAL-CELLS AND SERUM INVITRO
DUDMAN, NPB
HICKS, C
LYNCH, JF
WILCKEN, DEL
WANG, J
[J]. ARTERIOSCLEROSIS AND THROMBOSIS, 1991, 11 (03): : 663 - 670
[10] Plasma homocysteine as a risk factor for vascular disease - The European concerted action project
Graham, IM
Daly, LE
Refsum, HM
Robinson, K
Brattstrom, LE
Ueland, PM
PalmaReis, RJ
Boers, GHJ
Sheahan, RG
Israelsson, B
Uiterwaal, CS
Meleady, R
McMaster, D
Verhoef, P
Witteman, J
Rubba, P
Bellet, H
Wautrecht, JC
deValk, HW
Luis, ACS
ParrotRoulaud, FM
Tan, KS
Higgins, I
Garcon, D
Medrano, MJ
Candito, M
Evans, AE
Andria, G
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 277 (22): : 1775 - 1781

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