Signal transduction via the growth hormone receptor

被引：215

作者：

Zhu, T ^{[1
]}

Goh, ELK ^{[1
]}

Graichen, R ^{[1
]}

Ling, L ^{[1
]}

Lobie, PE ^{[1
]}

机构：

[1] Inst Mol & Cell Biol, Singapore 117609, Singapore

来源：

CELLULAR SIGNALLING | 2001年 / 13卷 / 09期

关键词：

growth hormone; receptor; cytokine; signal transduction;

D O I：

10.1016/S0898-6568(01)00186-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Rapid progress has been made recently in the definition of growth hormone (GH) receptor signal transduction pathways. It is now apparent that many cytokines, including GH, share identical or similar signalling components to exert their cellular effects. This review provides a brief discourse on the signal transduction pathways, which have been demonstrated to be utilized by GH. The identification of such pathways provides a basis for understanding the pleiotropic actions of GH. The mechanisms by which the specific cellular effects of GH are achieved remain to be elucidated. (C) 2001 Elsevier Science Inc. All rights reserved.

引用

收藏

页码：599 / 616

页数：18

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