Telomerase and cancer - Kirk A. Landon - AACR prize for basic cancer research lecture

被引：59

作者：

Blackburn, EH ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA

来源：

MOLECULAR CANCER RESEARCH | 2005年 / 3卷 / 09期

关键词：

D O I：

10.1158/1541-7786.MCR-05-0147

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：477 / 482

页数：6

共 10 条

[1] Extension of life-span by introduction of telomerase into normal human cells [J].

Bodnar, AG ;

Ouellette, M ;

Frolkis, M ;

Holt, SE ;

Chiu, CP ;

Morin, GB ;

Harley, CB ;

Shay, JW ;

Lichtsteiner, S ;

Wright, WE .

SCIENCE, 1998, 279 (5349) :349-352

[2] IDENTIFICATION OF A SPECIFIC TELOMERE TERMINAL TRANSFERASE-ACTIVITY IN TETRAHYMENA EXTRACTS [J].

GREIDER, CW ;

BLACKBURN, EH .

CELL, 1985, 43 (02) :405-413

[3] A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation [J].

Kim, MM ;

Rivera, MA ;

Botchkina, IL ;

Shalaby, R ;

Thor, AD ;

Blackburn, EH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (14) :7982-7987

[4] Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA [J].

Li, S ;

Crothers, J ;

Haqq, CM ;

Blackburn, EH .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (25) :23709-23717

[5] Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA [J].

Li, S ;

Rosenberg, JE ;

Donjacour, AA ;

Botchkina, IL ;

Hom, YK ;

Cunha, GR ;

Blackburn, EH .

CANCER RESEARCH, 2004, 64 (14) :4833-4840

[6] A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein [J].

Lin, J ;

Ly, H ;

Hussain, A ;

Abraham, M ;

Pearl, S ;

Tzfati, Y ;

Parslow, TG ;

Blackburn, EH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (41) :14713-14718

[7] Antitumor activity of systemically delivered ribozymes targeting murine telomerase RNA [J].

Nosrati, M ;

Li, S ;

Bagheri, S ;

Ginzinger, D ;

Blackburn, EH ;

Debs, RJ ;

Kashani-Sabet, M .

CLINICAL CANCER RESEARCH, 2004, 10 (15) :4983-4990

[8] Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis [J].

Weinstein, IB .

CARCINOGENESIS, 2000, 21 (05) :857-864

[9] Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules [J].

Xu, LF ;

Blackburn, EH .

JOURNAL OF CELL BIOLOGY, 2004, 167 (05) :819-830

[10] INVIVO ALTERATION OF TELOMERE SEQUENCES AND SENESCENCE CAUSED BY MUTATED TETRAHYMENA-TELOMERASE RNAS [J].

YU, GL ;

BRADLEY, JD ;

ATTARDI, LD ;

BLACKBURN, EH .

NATURE, 1990, 344 (6262) :126-132

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