Mechanism of hepatoprotective action of bile salts in liver disease

被引：31

作者：

Stiehl, A ^{[1
]}

Benz, C ^{[1
]}

Sauer, P ^{[1
]}

机构：

[1] Univ Heidelberg, Med Klin, Dept Med, Gastroenterol Unit, D-69115 Heidelberg, Germany

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 1999年 / 28卷 / 01期

关键词：

D O I：

10.1016/S0889-8553(05)70050-9

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Ursodeoxycholic acid (UDCA) improves liver enzymes and in many instances liver histology in cholestatic liver diseases such as primary biliary cirrhosis and primary sclerosing cholangitis. Besides classic cholestatic diseases, UDCA also improves liver biochemistry in alcoholic Liver disease and in chronic viral hepatitis C. The main target of UDCA treatment, however, is cholestasis, and consequently the mechanisms responsible for the beneficial effects in these diseases are ol: interest, and are discussed in detail in this article.

引用

页码：195 / +

页数：16

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