Do untreated bednets protect against malaria?

被引:111
作者
Clarke, SE
Bogh, C
Brown, RC
Pinder, M
Walraven, GEL
Lindsay, SW
机构
[1] Danish Bilharziasis Lab, DK-2920 Charlottenlund, Denmark
[2] MRC Labs, Banjul, Gambia
[3] Univ Durham, Sch Biol & Biomed Sci, Durham DH1 3LE, England
关键词
malaria; Plasmodium falciparum; disease control; vector control; bednets; children; poverty; The Gambia;
D O I
10.1016/S0035-9203(01)90001-X
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Bednets are thought to offer little, if any, protection against malaria, unless treated with insecticide. There is also concern that the use of untreated nets will cause people sleeping without nets to receive more mosquito bites, and thus increase the malaria risk for other community members. Regular retreatment of nets is therefore viewed as critical for malaria control. However, despite good uptake of nets, many control programmes in Africa have reported low re-treatment rates. We investigated whether untreated bednets had any protective benefit (in October and November 1996) in The Gambia where nets, although widely used, are mostly untreated. Cross-sectional prevalence surveys were carried out in 48 villages and the risk of malaria parasitaemia was compared in young children sleeping with or without nets. Use of an untreated bednet in good condition was associated with a significantly lower prevalence of Plasmodium falciparum infection (51% protection [95% CI 34-64%], P < 0.001). This finding was only partly explained by differences in wealth between households, and children in the poorest households benefited most from sleeping under an untreated net (62% protection [14-83%1, P = 0-018). There was no evidence that mosquitoes were diverted to feed on children sleeping without nets. These findings suggest that an untreated net, provided it is in relatively good condition, can protect against malaria. Control programmes should target the poorest households as they may have the most to gain from using nets.
引用
收藏
页码:457 / 462
页数:6
相关论文
共 30 条
[1]   A MALARIA CONTROL TRIAL USING INSECTICIDE-TREATED BED NETS AND TARGETED CHEMOPROPHYLAXIS IN A RURAL AREA OF THE GAMBIA, WEST-AFRICA .4. PERCEPTIONS OF THE CAUSES OF MALARIA AND OF ITS TREATMENT AND PREVENTION IN THE STUDY AREA [J].
AIKINS, MK ;
PICKERING, H ;
ALONSO, PL ;
DALESSANDRO, U ;
LINDSAY, SW ;
TODD, J ;
GREENWOOD, BM .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1993, 87 :25-30
[2]   A MALARIA CONTROL TRIAL USING INSECTICIDE-TREATED BED NETS AND TARGETED CHEMOPROPHYLAXIS IN A RURAL AREA OF THE GAMBIA, WEST-AFRICA .6. THE IMPACT OF THE INTERVENTIONS ON MORTALITY AND MORBIDITY FROM MALARIA [J].
ALONSO, PL ;
LINDSAY, SW ;
SCHELLENBERG, JRMA ;
KEITA, K ;
GOMEZ, P ;
SHENTON, FC ;
HILL, AG ;
DAVID, PH ;
FEGAN, G ;
CHAM, K ;
GREENWOOD, BM .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1993, 87 :37-44
[3]  
BOGH C, 1999, THESIS U COPENHAGEN, P20
[4]  
BOGH C, 1999, THESIS U COPENHAGEN, P40
[5]  
BRADLEY AK, 1986, LANCET, V2, P204
[6]   EFFECTS OF UNTREATED BED NETS ON THE TRANSMISSION OF PLASMODIUM-FALCIPARUM, PLASMODIUM-VIVAX AND WUCHERERIA-BANCROFTI IN PAPUA-NEW-GUINEA [J].
BURKOT, TR ;
GARNER, P ;
PARU, R ;
DAGORO, H ;
BARNES, A ;
MCDOUGALL, S ;
WIRTZ, RA ;
CAMPBELL, G ;
SPARK, R .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1990, 84 (06) :773-779
[7]  
CAMPBELL H, 1987, LANCET, V1, P859
[8]   INSECTICIDE IMPREGNATION CAN RESTORE THE EFFICIENCY OF TORN BED NETS AND REDUCE MAN-VECTOR CONTACT IN MALARIA ENDEMIC AREAS [J].
CARNEVALE, P ;
BITSINDOU, P ;
DIOMANDE, L ;
ROBERT, V .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1992, 86 (04) :362-364
[9]   The impact of charging for insecticide on the Gambian National Impregnated Bednet Programme [J].
Cham, MK ;
Olaleye, B ;
Dalessandro, U ;
Aikins, M ;
Cham, B ;
Maine, N ;
Williams, IA ;
Mills, A ;
Greenwood, BM .
HEALTH POLICY AND PLANNING, 1997, 12 (03) :240-247
[10]  
CLARKE SE, 1999, THESIS U COPENHAGEN, P104