β-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density:: Geelong osteoporosis study

被引：212

作者：

Pasco, JA

Henry, MJ

Sanders, KM

Kotowicz, MA

Seeman, E

Nicholson, GC

机构：

[1] Univ Melbourne, Dept Clin & Biomed Sci, Barwon Hlth, Geelong, Vic 3220, Australia

[2] Univ Melbourne, Austin & Repatriat Med Ctr, Dept Med, Melbourne, Vic, Australia

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 01期

关键词：

beta-blocker; fracture; bone densitometry; population studies; case-control studies;

D O I：

10.1359/JBMR.0301214

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This population-based study documented beta-blocker use in 59/569 cases with incident fracture and 112/775 controls. OR for fracture associated with beta-blocker use was 0.68 (95%CI, 0.49-0.96). beta-Blockers were associated with higher BMD at the total hip (2.5%) and UD forearm (3.6%) after adjusting for age, anthropometry, and thiazide use. beta-Blocker use is associated with reduced fracture risk and higher BMD.

引用

收藏

页码：19 / 24

页数：6

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