17 beta-(3-furyl)-5 beta-androstane-3 beta,14 beta,17 alpha-triol (PST 2238). A very potent antihypertensive agent with a novel mechanism of action

被引：55

作者：

Quadri, L

Bianchi, G

Cerri, A

Fedrizzi, G

Ferrari, P

Gobbini, M

Melloni, P

Sputore, S

Torri, M

机构：

[1] UNIV MILAN,HOSP SAN RAFFAELE,NEPHROL CLIN,I-20132 MILAN,ITALY

[2] UNIV MILAN,HOSP SAN RAFFAELE,DEPT BIOMED SCI & TECHNOL,I-20132 MILAN,ITALY

[3] PRASSIS IST RIC SIGMA TAU,DEPT CELLULAR BIOL,I-20019 SETTINO MILANESE,MI,ITALY

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1997年 / 40卷 / 11期

关键词：

D O I：

10.1021/jm970162e

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：1561 / 1564

页数：4

共 19 条

[1]

Barber B. R., 1994, V16, P316

[2] SODIUM IONS, CALCIUM-IONS, BLOOD-PRESSURE REGULATION, AND HYPERTENSION - REASSESSMENT AND A HYPOTHESIS [J].

BLAUSTEIN, MP .

AMERICAN JOURNAL OF PHYSIOLOGY, 1977, 232 (05) :C165-C173

[3]

BROWN L, 1984, ARZNEIMITTEL-FORSCH, V34-2, P1314

[4] DAHLS HYPOTHESIS THAT A SALURETIC SUBSTANCE MAY BE RESPONSIBLE FOR A SUSTAINED RISE IN ARTERIAL-PRESSURE - ITS POSSIBLE ROLE IN ESSENTIAL-HYPERTENSION [J].

DEWARDENER, HE ;

MACGREGOR, GA .

KIDNEY INTERNATIONAL, 1980, 18 (01) :1-9

[5] OUABAIN-LIKE FACTOR IN MILAN HYPERTENSIVE RATS [J].

FERRANDI, M ;

MINOTTI, E ;

SALARDI, S ;

FLORIO, M ;

BIANCHI, G ;

FERRARI, P .

AMERICAN JOURNAL OF PHYSIOLOGY, 1992, 263 (04) :F739-F748

[6] NA plus /K plus /CL--COTRANSPORTER MEDIATED RB plus FLUXES IN MEMBRANE-VESICLES FROM KIDNEYS OF NORMOTENSIVE AND HYPERTENSIVE RATS [J].

FERRANDI, M ;

SALARDI, S ;

PARENTI, P ;

FERRARI, P ;

BIANCHI, G ;

BRAW, R ;

KARLISH, SJD .

BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1021 (01) :13-20

[7]

FERRANDI M, 1996, HYPERTENSION, V28, P1010

[8]

GOTO A, 1992, PHARMACOL REV, V44, P377

[9] PRESENCE OF A POTENTIAL-SENSITIVE NA+ TRANSPORT ACROSS RENAL BRUSH-BORDER MEMBRANE-VESICLES FROM RATS OF THE MILAN HYPERTENSIVE STRAIN [J].

HANOZET, GM ;

PARENTI, P ;

SALVATI, P .

BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 819 (02) :179-186

[10] DEVELOPMENT OF AN IMMUNOASSAY FOR ENDOGENOUS-DIGITALIS-LIKE-FACTOR [J].

HARRIS, DW ;

CLARK, MA ;

FISHER, JF ;

HAMLYN, JM ;

KOLBASA, KP ;

LUDENS, JH ;

DUCHARME, DW .

HYPERTENSION, 1991, 17 (06) :936-943

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